Pig Brain Atlas

This website contains the three-dimensional MRI-based averaged brain and atlas of the neonatal piglet (Sus scrofa). This project is a collaboration between the Beckman Institute for Advanced Science and Technology and ACES Department of Animal Science at the University of Illinois Urbana-Champaign.

1. Register

We would like to create a database of those interested in piglet imaging. Please provide your name, email, and affiliation prior to download.

2. Download

After registering, you will be given the link to download the atlas as well as additional information on the software required.

3. Use

All of the files are in NIfTI format and can be viewed in a variety of available software (FSL, SPM, ect.).

High-resolution magnetic resonance imaging-based atlases for the young and adolescent domesticated pig (Sus scrofa)

Published: April 15, 2021
Atlas version: 2.0

Abstract

Background

Neurodevelopmental studies utilize the pig as a translational animal model due to anatomical and morphological similarities between the pig and human brain. However, neuroimaging resources are not as well developed for the pig as they are for humans and other animal models. We established a magnetic resonance imaging-based brain atlas at two different ages for biomedical studies utilizing the pig as a preclinical model.

New Method

Twenty artificially-reared domesticated male pigs (Sus scrofa) and thirteen sow-reared adolescent domesticated male pigs (Sus scrofa) underwent a series of scans measuring brain macrostructure, microstructure, and arterial cerebral blood volume.

Read the complete article.


An In Vivo Three-Dimensional Magnetic Resonance Imaging-based Averaged Brain Collection of the Neonatal Piglet (Sus scrofa)

Published: September 25, 2014
Atlas version 1.2

Abstract

Due to the fact that morphology and perinatal growth of the piglet brain is similar to humans, use of the piglet as a translational animal model for neurodevelopmental studies is increasing. Magnetic resonance imaging (MRI) can be a powerful tool to study neurodevelopment in piglets, but many of the MRI resources have been produced for adult humans. Here, we present an average in vivo MRI-based atlas specific for the 4-week-old piglet. In addition, we have developed probabilistic tissue classification maps. These tools can be used with brain mapping software packages (e.g. SPM and FSL) to aid in voxel-based morphometry and image analysis techniques. The atlas enables efficient study of neurodevelopment in a highly tractable translational animal with brain growth and development similar to humans.


Read the complete article.